Cytomorphology of normal, reactive, dysmorphic, and dysplastic megakaryocytes in bone marrow aspirates

This paper aims to emphasize the importance of applying international consensus guidelines detect qualitative and quantitative abnormalities megakaryocytes on smears bone marrow aspirates (BMA) for a shared harmonized diagnostic path between different laboratories. Careful evaluation BMA represents cornerstone in diagnosis most clonal nonclonal hematological diseases. Images associated with detailed morphologic description normal, reactive, abnormal, dysplastic are also reported together examples similar cells that, if not promptly identified, can lead morphological misdiagnosis.